by Srila B.B. Tirtha Goswami Maharaja
Sree Sree Guru Gaurangau Jayatah!
Even if we, by previous eternal good deeds, come in contact with a true devotee, we cannot submit to him sincerely and whole heartedly. It is very difficult to give up our mundane egotism which we have acquired by cycles of births and deaths after being averse to Sri Krishna.
Repugnance to the service of Sri Krishna and his devotees is the cause of nescience. Nescience, i.e., ignorance is the cause of misidentification of self. Misidentification of self is the cause of material desires. Material desires are the cause of committing sins. Committing sins is the cause of suffering. So the root cause of suffering is averseness to serve Sri Krishna.
The root cause of our afflictions is forgetfulness of our relation with Sri Krishna.